Explainers, news analysis and practical tracking guidance from the Peptimize team. Educational only - not medical advice. For compound references and study summaries, see the Research Library.
New kidney research is expanding the semaglutide conversation beyond weight loss. Explore the FLOW and REMODEL findings, their limits, and what to track with Peptimize.
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Can semaglutide improve knee osteoarthritis pain? Explore the STEP 9 evidence, its limits, and how Peptimize can help organize your medication and weight history.
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Can tirzepatide improve obstructive sleep apnea? Explore the Zepbound evidence, what it means for CPAP, and how Peptimize can support your next clinical review.
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New CagriSema results have renewed comparisons with tirzepatide. Learn why dose, diabetes status and trial design matter, and how to track your own treatment with Peptimize.
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STEP Young reported that 40.4% of children ages 6–11 treated with semaglutide and lifestyle support moved below the obesity threshold at 68 weeks. Here is what the topline result means, what remains unknown and what families should track with a specialist.
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Retatrutide has shown substantial weight-loss potential, but has it been proven better than tirzepatide? Compare the evidence, limitations and practical tracking questions.
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Compounded semaglutide and tirzepatide are back in the headlines. Learn what to verify with your pharmacist and how Peptimize helps organize your daily records.
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The first month on Foundayo involves more than watching the scale. Learn what to expect, how to keep track of side effects and appetite changes, and how Peptimize can help you build a clearer picture of your treatment experience.
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Feeling tired during GLP-1 treatment? Explore possible causes of fatigue and learn how Peptimize can help you organise symptoms for your next clinician review.
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Noticing hair loss on a GLP-1? Learn what recent research shows and how Peptimize can help organize your treatment, weight and symptom history for a clinician.
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GLP-1 microdosing is gaining attention. Explore the 2026 survey, weight-maintenance research, safety concerns and what lower-dose evidence actually shows.
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What the 2026 survodutide trials reveal about weight loss and liver fat—and why imaging changes, MASH improvement and fibrosis are different outcomes.
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Explore muscle preservation during GLP-1 treatment, the difference between lean mass and strength, and new clinical trial findings.
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MariTide pairs GLP-1 activation with GIP receptor blockade. Explore the monthly-treatment trials, new brain research and questions still awaiting answers.
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CagriSema combines amylin and GLP-1 biology in one investigational treatment. Explore its receptor mechanisms, clinical trial results, and what remains uncertain.
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Foundayo represents a different approach to GLP-1 therapy: a nonpeptide small molecule designed for oral administration. This review examines the pharmacology, clinical evidence, and implications of orforglipron.
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Retatrutide combines GIP, GLP-1 and glucagon receptor activity in a single investigational therapy. This review examines its mechanism, clinical evidence and unanswered questions.
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Sulfur-smelling burps are commonly discussed by people taking Mounjaro, Zepbound, Wegovy and other GLP-1 therapies. Here is what current evidence tells us about belching, delayed gastric emptying, hydrogen sulfide and when gastrointestinal symptoms deserve medical attention.
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Food noise can return during GLP-1 treatment without necessarily meaning the medication has stopped working. Learn what to track and when to discuss changes with your healthcare provider.
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A slowing or temporary stop in weight loss does not necessarily mean your GLP-1 has stopped working. Research with semaglutide and tirzepatide shows that weight plateaus are an expected part of long-term treatment. Here is what is worth tracking when the scale stops moving.
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Experiencing no nausea, constipation, or other side effects on a GLP-1 medication does not necessarily mean treatment is ineffective. Clinical evidence suggests that weight reduction with semaglutide and tirzepatide occurs even in people who do not experience gastrointestinal adverse effects.
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Appetite suppression can feel different as GLP-1 treatment continues. A return of hunger does not automatically mean your medication has stopped working. Here is what current research suggests and what information is worth tracking before discussing the change with your healthcare provider.
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A GLP-1 dose increase can feel like the beginning of a new phase of treatment. Learn what may change after titration and what is worth tracking around your medication, appetite, side effects, injections, and weight.
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Moving from semaglutide to tirzepatide can create a new chapter in your GLP-1 journey. Here is what is worth tracking so you can compare appetite, side effects, doses, weight trends, and treatment changes over time.
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Reaching your goal weight on a GLP-1 is a major milestone, but it is not necessarily the end of your journey. Here is what may come next and what is worth tracking during maintenance.
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Your weekly GLP-1 injection takes only a few moments, but recording the right details can create a much more useful treatment history. Here is what is actually worth tracking on injection day.
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Wondering if your GLP-1 is working? Discover 8 ways to track GLP-1 progress beyond weight, including appetite, side effects, measurements, medication history, and non-scale victories with Peptimize.
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Taking Ozempic, Wegovy, Mounjaro, Zepbound, Foundayo or another GLP-1 medication? Learn how to track side effects, injections or daily medication, doses and weight changes, and use Peptimize to identify patterns in your GLP-1 journey over time.
· Peptimize Editorial